Russian cosmonaut Yuri Malenchenko married his American girlfriend by video link between the ISS and Nasa space control in Houston.
Bride Yekaterina Dmitriyeva wore a traditional ivory wedding dress, while her husband wore a bright blue space suit with a bow tie.
His best man was fellow astronaut Edward Lu who played the wedding march on a portable keyboard.
And so she didn't feel too lonely, the bride stood next to a cardboard cut-out of her groom.
The couple wanted to get married in the same room, but Yuri's space mission was extended, so they decided to have a space wedding.
They've sold the video of their wedding to an American TV company, so the unusual service will be shown there on Monday night.