It was always going to be tough for Newcastle, taking on Manchester United in their first game back in the Premier League.
Dimitar Berbatov got the first goal for United, firing the ball past Newcastle keeper Steve Harper on 33 minutes.
Eight minutes later, Darren Fletcher doubled their lead with this close-range effort.
Goal of the night was from Ryan Giggs, who volleyed the ball into the net from a Paul Scholes cross, with 5 minutes left.
Ryan Giggs has now scored in every Premier League season since 1992. His goal completed a 3-0 win and a perfect start to the season for United.