This comes just a day after another US rapper, Nelly, revealed a seven-date tour of the UK, which he postponed because his sister was ill earlier this year.
50 Cent's gigs will take place on:
25 September - Wembley Arena, London
1 October - Birmingham NEC
8 October - Manchester MEN Arena
The rapper, who's had massive hits with In Da Club and 21 Questions, will be releasing a new single while he's on tour in the UK.
It won't be the first time he's performed here.
In June, he played at one of Eminem's Anger Management gigs in Milton Keynes and got rave reviews.