Malignant lesions (KS) Pneumonia (PCP) Brain infections Gut infection (MAC) Risk of blindness (CMV) Thrush and herpes Tuberculosis Cancer of immune system

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Introduction The HIV virus Infection Early stages Aids develops Anti-HIV drugs

As the immune system becomes damaged, it loses its capacity to fight disease and infections can become life-threatening.

People who are HIV positive are more susceptible to widespread diseases such as tuberculosis, malaria, pneumonia and shingles. Their vulnerability increases as their CD4+ cell count drops.

HIV patients also become vulnerable to a host of "opportunistic infections". These are infections caused by common bacteria, funguses and parasites which healthy bodies can fight, but which can cause illness and in some cases death in people with damaged immune systems.

Some of these are likely to occur at higher CD4+ counts than others. Most become active below CD4+ counts of 200, the point where Aids develops.

If full medical care is available, patients can be given drugs which treat and guard against some of these infections, although these are sometimes expensive and can cause side effects.

Click on the graph to read about some of the most common infections which affect HIV patients

INFECTION RISKS AS CD4+ COUNT DROPS


Brain infections: HIV patients are also vulnerable to two infections commonly affecting the brain. Toxoplasmosis, caused by a parasite found in animals, can cause lesions on the brain. Cryptococcus - a fungus found in soil - most commonly causes meningitis, an infection of the lining of the spinal cord and brain which can cause coma and death. These infections are most common in people whose CD4+ counts are below 100.

Symptoms: Headaches, fever, vision problems, nausea and vomiting (both), weakness on one side of the body, difficulty speaking and walking (toxoplasmosis), stiff neck (meningitis).

HIV GLOSSARY
What is a CD4+ CELL?

Guide to key HIV terms

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