A £38m scheme aims to revitalise sea fronts and town centres across north Wales to attract investment.
Over four years, 14 projects in Bangor, Colwyn Bay, Rhyl, Caernarfon, Holyhead, Amlwch and Llangefni will benefit.
Plans include providing office space, improving CCTV and bringing vacant properties back into use.
Some £19m of funding will come from the European Union with further cash provided by other sources such as the assembly government and local councils.
Leighton Andrews, deputy minister for regeneration, said: "The schemes will target town centres to ensure they will be in pole position to attract private sector investment when the economy improves."
Regeneration in Rhyl and Colwyn Bay will focus on developing the seafront to improve facilities and boost tourism, while town centre renewal projects have been proposed for Bangor and Caernarfon.
New quayside workshops and a pedestrian and cycle bridge to Kinmel Bay are some of the plans for Rhyl.
In Anglesey the funding will be used to renovate historic and derelict buildings, such as Llangefni Town Hall, and bring them back into economic use.
Clive McGregor, leader of Anglesey council, said: "The funding will allow us to forge ahead with a number of exciting regeneration schemes.
"The projects will help revitalise these towns by attracting visitors and creating much needed new employment opportunities."
The scheme aims to develop nearly three hectares of land in north Wales.
A total of £2.4m is earmarked for projects this year, and a further £35m will be paid between 2010 and 2013.
Mr Andrews said the programme would create "a more attractive climate for investment" in the area, while improving the environment for communities in north Wales.
European funding will be matched by the assembly government, four councils, Sustrans and the Heritage Lottery Fund.