Oscar-winning director Danny Boyle is to make his National Theatre debut directing a new production of Frankenstein.
The Slumdog Millionaire director will tackle Nick Dear's play, based on the novel by Mary Shelley, as part of the London theatre's winter season.
It is a return to the stage for Boyle who started his career in the theatre.
He directed plays for the Royal Court Theatre and the Royal Shakespeare Company (RSC), among others.
Sir Nicholas Hytner announced the National Theatre's plans for 2010 on Thursday.
Highlights include Marianne Elliott's production of Women Beware Women, Moira Buffini's new play Welcome to Thebes and Danton's Death directed by Michael Grandage.
Rory Kinnear will take on the title role in Sir Nicholas's production of Shakespeare's Hamlet, with Clare Higgins as Gertrude.
New plays by Mike Bartlett, Neil Bartlett and Handspring, Drew Pautz and JT Rogers are also planned.
Sir Peter Hall will direct Shakespeare's Twelfth Night, with Rebecca Hall as Viola, in a production in the Cottesloe Theatre to celebrate the RSC founder's 80th birthday.
Also in development are plans for the National to take part in the 400th anniversary celebrations of the King James Bible in 2011. Readings from the Gospels and the first five books of the Old Testament will be given by leading NT actors, past and present.