The creators of Wallace and Gromit, Aardman Animation, have agreed to make the Tate Gallery's first ever movie.
Independent charity Legacy UK has donated £3m to the animated project, which will be made by and for children across the UK.
They will be asked to create every aspect of the film, from the hand-drawn characters and plot twists, down to costumes and comic sound effects.
Tate director Nicholas Serota said the project was "uniquely ambitious".
He added: "Over the next two years we will collaborate with the best creative minds, professional and children's, on an unprecedented scale.
"Every child in Britain can be involved in The Tate Movie and we will help them to draw on their imaginations, lives and communities whilst developing their visual literacy, and inspiring the artists of the future."
Dave Sproxton, co-founder and chairman of Aardman Animations said: "This project will encourage school children to design characters and backgrounds, record sounds and voices and contribute individually to this exciting prospect.
"We want children to be involved at every level and believe that the spontaneity and creativity of the children combined with our professional film making team will create a film that is as inspiring as it is entertaining."
Production workshops will run around the country and children will also be able to contribute their ideas on an interactive website.