Twenty Labour MPs have pledged to fight plans to move the National Football Museum from Preston in Lancashire, and re-house it at the new Wembley Stadium.
The idea was suggested by Lord Mawhinney, the chairman of the Football League, and a former Conservative Cabinet Minister.
In a Commons motion the MPs said they "deplore" the idea of moving what they call "the crown jewels of football".
Preston had made a major contribution to football's history, they said.
Preston North End was one of the 12 founder members of the Football League in 1888, becoming the first team to do the League and FA Cup "double", with Deepdale being the oldest professional football ground in the world.
The exhibits at the musuem include: the ball from the 1966 World Cup Final, a replica of the Jules Rimet Trophy and the England captain's jersey and cap from the world's first official international football match when England played Scotland in 1872.
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