Nicholas Edwards, 39, is accused of the rape of one woman but five others have come forward making similar allegations and will be called as witnesses.
He denies raping a 23-year-old woman Miss D in his flat in 1998 and says she was a willing partner.
His trial is the first in which the jury has been allowed to hear evidence of "strikingly similar" alleged date rape attacks going back several years.
Prosecuting counsel David Perry said date-rape allegations had been produced so that the jury would not have to rely on just one woman's word against that of Edwards.
Edwards has admitted that a seventh woman has also accused him of rape.
He served a five-year sentence after being convicted of rape in 1986 and was also acquitted of a similar offence, alleged by another woman.
Edwards maintained that the women made "false, malicious and spiteful," allegations against him for a variety of different reasons.
When questioned as to why so many women had made allegations against him, he replied: "Why does this keep happening to me, it is so unfair".
Edwards told an Old Bailey jury that he sometimes needed to have chaperones because it was a risk for him to be alone with women.
"I had to have one or two female friends so that at the end of the day I didn't have this type of trouble from women", he told the court.
However, he agreed that he did not tell detectives who questioned him about the 1998 alleged rape that similar complaints had been made before by other women.
The case continues.