Speaking in her first interview since his conviction last month, Mary Archer told BBC Radio 4's Today programme that she did not find it difficult to stand by him and would continue to do so.
She also said that she stood by every word she said gave in evidence during Lord Archer's Old Bailey trial.
The former Tory party deputy chairman, 61, was sentenced to four years' imprisonment after being found guilty on two counts of perjury and two counts of perverting the course of justice.
He was cleared of one count of perverting the course of justice.
The Old Bailey jury decided that he had lied and cheated in his 1987 libel case against the Daily Star, which had printed a story claiming he had slept with prostitute Monica Coghlan.
He was initially sent to the high-security Belmarsh Prison in south-east London, where he spent three weeks before being transferred to Wayland Prison near, in Norfolk, a category C jail.
The decision was made not to send him to an open prison following news of a new police inquiry into the millionaire novelist's financial affairs.
'Open season'
Former Conservative MP Emma Nicholson has called for the Fraud Squad to look into what happened to millions of pounds raised by Lord Archer for the Kurdish people of northern Iraq.
Asked about her husband's welfare, Lady Archer said: "He is bearing up well, though he is anxious to be in an open prison where he should be."
Speaking about his day-to-day routine, she said it was a private matter but added: "The prison regime is rather a good one for a writer. You have plenty of time to write."
Commenting on the trial and if she found it difficult to stand by her husband, she said it had been "a very difficult period" but said she did not find it difficult to stand by him.
Asked if she would continue to do so, she replied: "Indeed."
She said that since the trial it had been "open season" in the newspapers on her and her family and she was now glad to move on.
She also denied reports that she was planning to sell her story for £250,000, saying she was "not in the business of writing my story".
She added: "That's not going to happen."
There were reports after Lord Archer's conviction that Lady Archer could be questioned and even face prosecution over the evidence she gave during his Old Bailey trial.
"I would be amazed and astounded if I were to be. I stand by every word I said," she said.
She added that she had not spoken to the police or anyone else about possible charges.
She confirmed that an appeal against Lord Archer's conviction was lodged last week and the next step was to get permission to go ahead with it.
"I do expect to be given that permission," she said.