The Australian wine company, BRL Hardy, unveiled a world-first security seal on Thursday, which uses DNA coding to authenticate its flagship wine.
The seal is based on a DNA identification process used on tickets for the Sydney Olympics.
The move comes after a series of high-profile fraud cases, such as the 1998 discovery of fake bottles of the country's leading premium wine Penfolds Grange.
BRL Hardy's international marketing manager Jim Humphrys said the spate of thefts and forgeries had prompted the company to explore DNA identification.
"If you're a collector and you buy a dozen of these, you're going to spend well over $1,000 [£370] and you don't want to turn around in three or four years' time and find out you've been sold a dud."
Hi-tech solution
DNA from the company's 125-year-old vines in south Australia is impregnated into light-reflective ink and applied to a tamperproof neck label that will seal the bottle.
Security measures to authenticate stock will include random and pre-sale checks at auction houses and at wine retailers, and customer enquiries will be checked on request.
Super plonk
The seal will be on bottles of the Eileen Hardy shiraz from 1 August when the company releases the 1998 vintage.
The company produces 3,000 to 6,000 cases of Eileen Hardy each year, which sells for between £40 to £50 a bottle in the UK.
The company's red winemaker Steven Pannell said wine was an increasingly popular investment.
"Sadly this has led to an increase in wine fraud with our industry."
Wine companies around the world have introduced anti-tamper devices such as special cork seals and laser etching on bottles to prevent thieves from forging premium wines.