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BBC News Online: Health


Monday, 14 May, 2001, 23:16 GMT 00:16 UK

Malaria drug 'easier for tourists'


Maralone is said to be more convenient
A treatment to prevent malaria launched in the UK this week may make life simpler for travellers - but at a price.

Malarone can be taken only one day before a traveller flies to a country in which malarial mosquitoes are common, and is an alternative to other popular anti-malarials such as Lariam.

Almost half of those who visit malaria-prone countries have not bothered to take prophylactic treatments against the disease.

A single bite from a mosquito can leave them infected.



It's possible to die within 24 hours of developing the first symptom
Dr Richard Dawood, travel health expert

There are more than 2,000 cases a year diagnosed in this country - many of which do not emerge until some weeks after the traveller has returned to the UK.

Malaria is fatal in a small number of cases in this country, causing serious illness and even lasting disability in many others.

It is caused by a microscopic parasite which can be passed into humans when they are bitten by various types of mosquitoes.

Malarone is a combination of two existing anti-malarial drugs, and can target the parasite which causes the illness at two stages of infection while it is both in the liver, and in the bloodstream.

Horror story

Angela Green, who survived a bout of malaria following a single mosquito bite during a trip to Africa, is still feeling the after-effects.

"My body's circulation system shut down, my liver and kidneys weren't working, and I had no feeling in my legs and feet.

Angela Green
"That was my lowest point - and afterwards they told me that I nearly died then.

"Even after I came out of hospital, I couldn't walk, was extremely tired - I lost my toenails."

"If I meet anyone who says they are going to these countries without taking anti-malaria drugs, I tell them they are absolutely mad."

GlaxoSmithKline, which manafactures Malarone, says the drug is 97% effective against the parasite.

However, the drug is considerably more expensive than Lariam, the standard anti-malarial currently available at travel clinics.

Malaria remains a major killer disease in a large number of countries, despite efforts at eradication involving swamp clearance and insecticides to reduce the numbers of the mosquitoes.

Dr Richard Dawood, a specialist in travel medicine and editor of Traveller's Health magazine, said: "Most people might not realise how rapidly malaria can progress.

"It's possible to die within 24 hours of developing the first symptoms."


Related to this story:
The anti-malaria drug dilemma (15 May 01 | Health) Malaria (26 Jul 99 | Medical notes) Travel sick: what you can catch (31 May 00 | Health) Africans genetically susceptible to malaria (28 Jun 00 | Health) Venom to arm mosquito against malaria (05 Jul 00 | Health)


Internet links: London School of Hygiene and Tropical Medicine | Travel Health.co.uk | Glaxo SmithKline |
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