LeRoi Moore, a founding member of the Dave Matthews Band, has died aged 46, his publicist has said.
The versatile saxophonist died after suffering complications from injuries sustained in a vehicle accident in June on his Virginia farm.
Publicist Ambrosia Healy said he died on Tuesday at Hollywood Presbyterian Medical Center, in Los Angeles.
A statement announcing the star's unexpected death on the band's website said: "We are deeply saddened".
Classically trained
Moore initially went to hospital in June after crashing an all-terrain vehicle on his farm outside Charlottesville, Virginia.
He was later discharged and had returned to his Los Angeles home to begin a physical rehabilitation program when complications forced him back to the hospital in July.
"It's always easier to leave than be left"
He was classically trained but said jazz was his main musical influence, according to a biography on the band's web site.
The group formed in 1991 in Charlottesville, Virginia, when lead singer Dave Matthews was working as a bartender.
He handed a demo tape of his songs to Moore, who liked what he heard and recruited his friend and fellow jazzman Carter Beauford to play drums.
The group broke out of the local music scene with the album Under the Table and Dreaming.
They went on to win a Grammy award in 1997 for the hit song So Much to Say, from their second album Crash.
Other hits include What Would You Say, Crash Into Me and Satellite.
The band went on with its show Tuesday night at the Staples Center in Los Angeles, where lead singer Dave Matthews dedicated the entire show to Moore.
"It's always easier to leave than be left," Matthews told the crowd, according to Ambrosia Healy, the band's publicist.
"We appreciate you all being here."
Saxophonist Jeff Coffin had been sitting in for Moore during the band's summer tour.
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