Statisticians at the National Statistics office have, in a social and economic survey, identified that people in the south are better off than those in the north.
But while London and the south-east of England contribute almost one-third of the UK's economic muscle, their population's main advantage is in health terms, the report says.
The survey, published on Thursday, also identifies a behavioural divide, with Northern Ireland as Britain's most sober region.
Booming Bracknell
London, eastern England and south-eastern counties, stretching from Oxfordshire to Kent, are the only UK regions where economic production exceeds the national average, the report shows.
(Relative GDP, per head)
The south-east also includes Britain's best-paid employees, with one-in-10 Bracknell Forest men earning more than £59,000 per year, compared with a national average salary of £20,732.
The average annual wage in Northern Ireland is £17,900. In north Yorkshire, one-in-10 men earns less than £10,000 a year, with average earnings for Yorkshire and Humber workers at £18,800.
The report acknowledges regional differences in income, housing costs and unemployment.
Digging deep
But the survey, the latest Regional Trends report, also warns against taking headline data at face value.
(Relative GDP, per head)
"Household expenditure and housing costs for those living in the south are higher than the national average and house prices continue to rise at a faster rate," says the report.
House prices rose at 17% between 1998-99, compared to 6-7% in the north of England and the East Midlands.
The figures also conceal "considerable variability within regions", the report says. Although 10% of Londoners earn more than £50,000, 10% earned less than £12,600.
Health gap
The north-south health divide is seen in the statistic that 10% more northern and Scottish women than southern females die of heart failure.
"In particular, deaths from circulatory diseases are much higher in the north," says the report.
Glasgow, Halton, Merthyr Tydfil and Blyth Valley are identified as health blackspots.
Levels of alcohol consumption also varied markedly between the north west and the south and east, with Northern Irish people "by far" the most abstemious.
"Almost half of men and three-fifths of women in Northern Ireland had not had an alcoholic drink in the week prior to the interview," the report says.
Factory link
The differing rates of economic activity between north and south reflect the regions' reliance on manufacturing.
More than one quarter of GDP produced by Northern and Midland counties comes from manufacturers.
In the south-east, manufacturers produce 16.2% of GDP, and in London the figure is below 12%.
In schooling, Scotland, where 30.4% of people are qualified to Higher level, has the best-educated population. Fewer than one-in-five Londoners has any A-levels.
The north-east is the safest region to drive in, with most accidents per head of the population in the East Midlands and London.