The first European flight to benefit from the US and European Union "open skies" deal will take off from London's Heathrow airport later.
An Air France plane is due to leave London for Los Angeles at 1700 GMT. It is the first of three new transatlantic routes operated with US airline Delta.
It marks a new era in air travel as limits on which airlines can fly between the US and EU come to an end.
The first open skies New York to London flight landed at Heathrow on Sunday.
The service was operated by Continental Airlines, the fifth largest US airline.
Cheaper flights?
It was one of many airlines previously prevented from operating to Heathrow, a key hub for international travel under a number of bilateral deals dating back 30 years.
Until the weekend, this prized route was the sole preserve of British Airways, Virgin Atlantic, United Air Lines and American Airlines.
OPEN SKIES: WHAT DOES IT MEAN?
The new rules are expected to lead to a large rise in the number of carriers on the routes and there are already signs of this.
For April, scheduled flights from the EU to the US have jumped by 11% on the same month last year, according to the International Air Transport Association (IATA).
The highest rise in traffic is observed from London, where the number of scheduled flights has jumped by 25% to 640 from 511.
Analysts also expect prices to come down as a result, although it widely believed the benefits will be felt by business travellers rather than economy fliers, where firms will struggle to bring down costs as a result of high fuel bills.
Other changes
Under the new rules, US airlines can now buy a stake of up to 49% in their European rivals.
But European airlines will still only be able to buy 25% in US carriers.
EU Transport Commissioner Jacques Barrot has pledged to improve that deal, and says if he does not get parity he will roll back some of the open skies agreements from 2010.
IATA has argued that the next round of talks must "address the liberalisation of ownership rules so that airlines can merge or consolidate where it makes business sense."
Giovanni Bisignani, IATA’s director general and chief executive said: "Every other industry has the opportunity to go global. Why not the airlines?"
^ Back to top | BBC Sport Home | BBC Homepage | Contact us | Help | ©