A BBC correspondent in Davos, Patrick Bartlett, says the internet is in some sense the last frontier in the process of globalisation.
Bill Gates of Microsoft and Pierre Omidyar, the founder and Chairman of eBay, will be among those attempting to provide answers.
On Sunday a video debate between participants of the WEF in Davos and anti-globalisation summit, the World Social Forum, taking place concurrently in the Brazilian city of Porto Alegre, degenerated into a slanging match.
Earlier on Sunday, organisers of the World Social Forum announced that they intend to make the anti-Davos meeting an annual event.
Key questions expected to be addressed on Monday include how the internet can be policed, who will tax the goods traded on it and how mobile phones will change digital communication.
A BBC correspondent in Davos, Patrick Bartlett, says the internet is in some sense the last frontier in the process of globalisation.
Who should have responsibility for controlling web content is a key question on the agenda in Davos.
The recent legal ruling in France ordering internet service provider, Yahoo, to prevent access to sites auctioning neo-Nazi memorabilia has sent shock waves through the industry.
Internet trade tax
As the internet becomes an increasingly important trading tool, industry leaders will be debating how, or whether, products sold on the net should be taxed and who should be entitled to levy the tax.
Just one person in 10 living in the world has access to the internet.
With the demonstrations against globalisation fresh in their minds, industry leaders know they have to do more to spread the benefits of the new technology.
Annan warning
Also on Sunday, UN Secretary-General Kofi Annan called on business to work harder on environmental and social issues.
He warned delegates in Davos that unless business did so, the backlash against globalisation could gain momentum.
His call followed Saturday's anti-globalisation protests in Davos, which were quashed by riot police.
In Zurich there were serious clashes between police and anti-globalisation protesters late on Sunday.
More than 120 demonstrators were arrested.
The protesters were angry at being turned back after trying to reach the World Economic Forum.
Demonstrators hurled paving stones and bottles at police who replied with tear gas, water cannon and plastic bullets.