Welsh Labour has suffered humiliation in the European elections, with the Conservatives topping the poll.
It is the first time since 1918 Labour has failed to come first in a Welsh election, as its vote dropped by 12%.
Labour, Conservatives and Plaid Cymru won a seat each, as did the United Kingdom Independence Party, which will send its first Welsh MEP to Brussels.
First Minister Rhodri Morgan and Welsh Secretary Peter Hain said Labour fell victim to anger over MPs' expenses.
2009 EURO ELECTION - WALES
Conservative: 145,193 (21.2%, up 1.8%)
Labour: 138,852 (20.3%, down 12.2%)
Plaid Cymru: 126,702 (18.5%, up 1.1%)
UKIP: 87,585 (12.8%, up 2.3%)
Lib Dems: 73,082 (10.7%, up 0.2%)
Greens: 38,160 (5.6%, up 2%)
BNP: 37,114 (5.4%, up 2.5%)
Christian Party: 13,037 (1.9%)
Socialist Labour Party: 12,402 (1.8%)
No2EU Yes to Democracy: 8,600 (1.3%)
Jury Team: 3,793 (0.6%)
Turnout: 30.4% (down 11%)
Wales' MEPs are Conservative Kay Swinburne, Labour's Derek Vaughan, Plaid Cymru's Jill Evans, and UKIP's John Bufton.
Nick Bourne, who leads the Tories in the Welsh assembly said: "This result kills the lie that Wales will always be Labour."
In 2004 Labour had won two of the four seats with 32% of the vote. But five years on Labour has seen its vote fall to just 20%.
The Tories edged ahead of Labour, and were up 1.8% to 21%, while Plaid improved its share by 1.1% to 19%.
But Liberal Democrats again suffered European disappointment. They have never had a Welsh MEP, and were pushed into fifth place, with 10.7%, up 0.2%.
Conservative Cheryl Gillan: People in Wales are thoroughly fed up with the Labour Party
Before the results were officially declared, Labour's top two figures in Wales said Labour, as the party in power, had "caught the brunt of the public's anger".
"This is a toxic combination when taken with the economic recession," said Mr Morgan and Mr Hain in a joint statement.
"Low turnout has further reduced the Labour vote. "Above all, we have got to listen to the message that the public is so clearly giving us.
"It is vital that Labour remains united and begins rebuilding trust.
"Our task is to clearly convey the choice that Wales now faces: between a Labour government that believes in Welsh people and helps during hard times, and the very real danger of a government led by David Cameron that would savagely cut public services.
Above all, we have got to listen to the message that the public is so clearly giving us... it is vital that Labour remains united and begins rebuilding trust
First Minister Rhodri Morgan and Welsh Secretary Peter Hain
Plaid Cymru MP Adam Price referred to an earthquake which hit south Wales on Friday night, adding: "We've had an even bigger one today.
"It's off the Richter scale, because the Labour Party hasn't lost an election in Wales since the khaki election of 1918: you've got to go back that long.
The Carmarthen East and Dinefwr MP said: "The political landscape has changed here. We've benefitted; we've had a good result, the Tories have had a very good result, but Labour... this is earth shattering for them".
'Imploding in heartlands'
He said Labour was "imploding in the hardest of its heartlands".
Earlier, retiring MEP and new Europe Minister Glenys Kinnock called it "a bad night for us".
WELSH PARTIES' PERFORMANCES IN PAST EUROPEAN ELECTIONS
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