Final preparations are being made for the demolition by controlled explosion of the landmark cooling towers at Chapelcross nuclear power station.
The four 300ft stacks are set to be brought down at 0900 BST on Sunday.
It is part of the decommissioning process at the plant, near Annan, which has dominated the skyline since 1959.
The demolition is expected to take only 10 seconds and will be broadcast live on the internet. A DVD of the event is also set to be produced.
A 200-metre exclusion zone will be enforced on the day and police road closures will be in place from 0700 BST until 1030 BST in the surrounding area.
Thousands of spectators are expected to turn out to witness the event.
Site director David Wilson appealed to the public to heed the restrictions in place.
"We have worked very closely with local police on this," he said.
"They have a plan in place to close various roads and put restrictions in place on others.
"We would urge the public to take notice of the police and the restrictions they have put in place."
He also asked people to remember that there were local people in the area who needed to go about their daily business.
"Please give these people the respect they deserve as well," said Mr Wilson.
"I think probably the best advice is to view it from as far away as you can."
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