Crack cocaine worth about £1m has been seized by Grampian Police in the past year - 10 times the total of all the other Scottish forces.
Police said the difficult fight against drugs would continue
Seizures of heroin in the region were worth another £1m.
Police said the seizures, mainly in Aberdeen, were thanks to creating a "hostile and unproductive environment" against drug syndicates.
Det Supt Alan Smith said: "The seized quantities of crack cocaine indicate that we have been hugely successful."
About 7kg of crack cocaine was seized in total after Operation Blaven was launched early in 2006, with a street value of £1m.
Crack was first seized in Grampian in 1996 and a rock now sells for up to £50 in the region.
Det Sup Smith said: "We are not naive and realise that enforcement alone is not the answer. There is on-going work with our partners to remove the scourge of the drug menace from our communities.
"We also accept that there can be no time limit to this effort as the syndicates we have targeted, and caused damage to, will simply regroup and reorganise.
"Grampian Police is committed to continuing in its efforts to disrupt the supply of Class A drugs to the North East of Scotland."
Head of Grampian Police drugs squad, Det Insp Colin Walker, added: "Quality intelligence showed that these syndicates perceived that Aberdeen in particular and the surrounding area were lucrative areas in which to ply their trade.
"They believe they can achieve greater profits and they are less likely to be confronted by violence in the North East of Scotland.
Operation Blaven was launched at the start of 2006
"Pro-active and intelligence-led policing has led to the interception of large quantities of drugs before they reached their intended markets within Grampian."
Grampian Police made the announcement as new figures showed seizures of Class A drugs throughout the region had risen.
There were almost 600 seizures in 2006 - with more than 450 of them involving heroin - according to the figures released by the Scottish Executive.
That compared to less than 500 hauls of Class A drugs during the previous 12 months.
North East Labour MSP Richard Baker said it showed the continued need for drug treatment services in the area.