Page last updated at 11:19 GMT, Wednesday, 24 March 2010

New drug hope in fight against TB

Tuberculosis bacteria
TB kills an estimated two million people worldwide each year

A compound which could form the basis of a new drug to treat tuberculosis (TB) has been discovered by a team led by the University of Strathclyde.

Researchers developed the compound from an antibiotic, which they hope could become an effective treatment for TB.

The compound will undergo further tests before it can be developed into a drug which can be tested on humans.

TB kills about two million people each year and some strains are now resistant to drugs currently used.

The research represents the first time a new class of anti-TB agent has been discovered solely by a UK-based academic collaboration.

It is also the first major breakthrough for Tuberculosis Drug Discovery UK (TBD-UK), a nationwide consortium of scientists specialising in the development of new medicines to treat TB.

Our research has found a promising scaffold for a new class of drugs to deal with this severe health problem
Dr Geoff Coxon
Strathclyde University

The group includes Strathclyde University, together with partners at University College London and the University of Birmingham.

The newly-published research was led by Dr Geoff Coxon, of the Strathclyde Institute of Pharmacy and Biomedical Sciences.

He said: "TB is a very complex disease. It's not only deadly in itself but is closely linked with HIV/AIDS. It's also very difficult to detect and treat.

"Globally, more than eight million people develop active TB every year and if trends continue, there will be a total of 36 million TB-related deaths by 2020 - yet the drugs used to treat the disease were developed in the 1950s.

"All of this highlights the urgent need for new, more effective drugs to treat it. Our research has found a promising scaffold for a new class of drugs to deal with this severe health problem."



Print Sponsor


SEE ALSO
In pictures: World TB Day
24 Mar 10 |  In Pictures
Vaccine 'could cut HIV TB deaths'
30 Jan 10 |  Health
HIV-TB 'double trouble' warning
24 Mar 09 |  Health
UV light 'could curb TB spread'
17 Mar 09 |  Health
Old drug combination in TB fight
27 Feb 09 |  Health

RELATED INTERNET LINKS
The BBC is not responsible for the content of external internet sites


FEATURES, VIEWS, ANALYSIS
Has China's housing bubble burst?
How the world's oldest clove tree defied an empire
Why Royal Ballet principal Sergei Polunin quit

BBC iD

Sign in

BBC navigation

Copyright © 2020 BBC. The BBC is not responsible for the content of external sites. Read more.

This page is best viewed in an up-to-date web browser with style sheets (CSS) enabled. While you will be able to view the content of this page in your current browser, you will not be able to get the full visual experience. Please consider upgrading your browser software or enabling style sheets (CSS) if you are able to do so.

Americas Africa Europe Middle East South Asia Asia Pacific