Keira Knightley and Matthew Rhys star in The Edge of Love
The 62nd Edinburgh International Film Festival (EIFF) will show 142 features from 29 countries during its 12 day run.
There will be 15 World premieres and 72 UK premieres.
The Opening Night Gala will see John Maybury's The Edge of Love starring Keira Knightley and Sienna Miller.
The festival closes with the World premiere of Faintheart, a comedy by Vito Rocco starring Eddie Marsan, Jessica Hynes and Ewan Bremner.
Among the other highlights are new films from Shane Meadows, Werner Herzog, Wayne Wang and Christopher Doyle.
Meadows will also appear as part of the In Person series of interviews, alongside cinematic luminaries such as local hero Brian Cox, legendary documentarian Errol Morris and special effects guru Ray Harryhausen.
The British Gala section features Stone of Destiny, charting the remarkable story of the 1950 theft of the Stone of Scone from Westminster Abbey.
Other British Galas in competition for the Michael Powell Award include Meadows' Somers Town, Oliver Blackburn's Donkey Punch and Matthew Thompson's Dummy.
International films include The Wackness, starring Sir Ben Kingsley.
The festival's artistic director Hannah McGill describes Irish comedian Dylan Moran's A Film with Me in It as "Shallow Grave meets Withnail & I".
Cinematographers such as Brian Tufano (Trainspotting), Roger Deakins (No Country for Old Men) and Seamus McGarvey (Atonement) are also featured in the In Conversation section of the festival.
Festival favourite Christopher Doyle brings his thriller Warsaw Dark to the festival for a World premiere.
Documentaries on show include Herzog's Encounters at the End of the World, James Marsh's Man on Wire and Errol Morris's dissection of the Abu Ghraib scandal, Standard Operating Procedure.
The Mirrorball strand features music films and promos from around the world, including the eagerly-awaited Gorillaz feature Bananaz.