The jail holds prisoners serving four years or more
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Two prisoners have been taken to hospital following a disturbance at Glenochil Prison.
More than a dozen inmates were involved in the incident, which lasted more than five hours.
The Scottish Prison Service (SPS) said an investigation had been launched into the disturbance in C Hall.
The two prisoners taken to hospital are believed to have been suffering from smoke inhalation.
The central Scotland jail is home to people serving sentences of four years or more.
A disturbance began at approximately 1550 BST on Friday when 14 prisoners began smashing up their cells.
Police investigation
The incident was resolved at about 2100 BST after prison officers in riot gear were called in to tackle the situation.
The SPS said it had launched an investigation into the incident.
"It would be inappropriate for us to comment further as the police are also investigating and criminal proceedings may follow," said a spokesperson.
The cause of the disturbance is not yet known.
An incident at the jail in 2000 was prompted by the seizure of heroin from a prison visitor.
Earlier this year a disturbance at Shotts Jail in Lanarkshire caused damage estimated at £1m.