The East Antrim seat has been won by the DUP's Sammy Wilson. Mr Wilson overwhelmingly defeated his UUP rival Roy Beggs by 15,766 votes to 8,462.
Sammy Wilson wins a landslide victory in East Antrim
The result is a landslide victory for the DUP which has been gaining ground on the UUP in the constituency.
It is also a huge increase on the 2001 result when the DUP came within 101 votes of unseating Mr Beggs.
Mr Wilson said, although he had been described as a blow-in, he had taken over 50% of the vote.
He added: "That is a picture of the general trend across Northern Ireland where the unionist population are looking as to who they can best put their trust in to deliver effective devolved government.
"Devolved government based on democratic principles not on shoddy compromise or vague ambiguity."
The departure of Mr Beggs, who has been an MP for 22 years, is another bitter blow for the UUP.
The party has also lost the South Belfast seat to the SDLP.
Speaking after the result was announced, Mr Beggs said the party would look at why they had not commanded the support of the electorate, but that their policies put Northern Ireland first and the desire for power second.
He said that he did not blame party leader David Trimble for his defeat and that they would have to "involve again all those who stayed at home".
A former member of the Democratic Unionist Party, Roy Beggs has been one of the most intractable opponents of the Good Friday Agreement.
He has opposed almost all concessions to nationalists and in 1995 was arrested and fined after inciting Orange Order members to block a road outside the port of Larne.
The former teacher spent a lot of time campaigning on improving school dinners during this election.
He is firmly Eurosceptic and a supporter of the re-introduction of both corporal and capital punishment.