Labour heavyweight Jacqui Smith lost her seat to the Tories
The Conservative Party has made sweeping gains in England, gaining 92 seats.
The Tories have ousted Labour from key target seats including Waveney, Dewsbury and Stafford, but failed to secure an overall UK majority.
Labour have lost 87 seats across England, and the Liberal Democrats have lost four, with results in for all but two constituencies.
The results so far indicate a 5.6% swing from Labour to the Conservatives.
The Conservative Party took 14 seats in the West Midlands, including former home secretary Jacqui Smith's
But they failed to win a number of key targets, including
which was held by Labour's Gisela Stuart with a majority of more than 1,000.
The Tories also gained 14 seats in the South East, 11 in the East Midlands and 10 seats in the North West.
But Labour held firm in its North East stronghold losing only two of its 25 seats - one to the Conservative Party and one to the Liberal Democrats.
Houghton and Sunderland South
was the first to declare results at 2252 BST. It was the fifth general election running it had been first to announce its next MP.
Labour's Bridget Phillipson won the seat with 19,137 votes.
Former home secretary Charles Clarke and former communities minister Shahid Malik were among notable Labour figures who lost their seats overnight.
Caroline Lucas became the Green Party's first MP after winning the
Ms Lucas told supporters they had "put the politics of hope above the politics of fear".
"For once the word historic fits the bill," she added.
Independent MP Dr Richard Taylor lost his seat to the Conservatives.
Mark Garnier won the Worcestershire seat of
with 18,793 votes, compared to Dr Taylor's 16,150.
Dr Taylor, who was one of two independent MPs in Parliament, was elected in 2001 based on a single issue campaign to save Kidderminster Hospital services.
In Nottinghamshire, former GMTV reporter Gloria De Piero successfully defended the Labour seat of
The breakfast show's former political editor was selected as the Labour candidate after former Defence Secretary Geoff Hoon stood down.
Conservative Zac Goldsmith won in Richmond Park
She took 16,239 votes, just 192 ahead of Jason Zadrozny of the Liberal Democrats.
Television presenter Esther Rantzen failed in her attempt to oust Labour from the
seat, polling 1,872 votes.
Labour's Gavin Shuker won 14,725 votes, a majority of 2,329 over Conservative candidate Nigel Huddleston.
Labour's Ed Balls narrowly won the new seat of
Morley and Outwood
with 18,365 votes, followed by Conservative Antony Calvert who gained 17,264 votes.
Liberal Democrat casualties included the party's science spokesman Dr Evan Harris, who narrowly lost his
Oxford West and Abingdon
seat to Conservative Nicola Blackwood.
Ms Blackwood polled 23,906 votes - 176 more than Dr Harris, who had held the seat since 1997.
millionaire environmentalist Zac Goldsmith successfully saw off the sitting Liberal Democrat MP Susan Kramer to take the seat for the Tories.
The Conservatives have taken 39.7% share of the vote in England, followed by Labour on 28.2%.
The Liberal Democrats stand on 24.1% of the vote, with UKIP fourth on 3.4%.