Police arrested 59 people and issued 144 anti-social behaviour warnings in a crackdown on drink-related crime across the Avon and Somerset force area.
Alcohol was seized from 82 under-18s during Operation Relentless on Friday night and the early hours of Saturday.
Licensing and trading standards checks were also made on 231 pubs, clubs and shops in the city.
Asst Ch Cons Steve Mortimore said reducing alcohol-fuelled crime was a day-to-day priority for officers.
'Huge responsibility'
"Our overall message could not be simpler - enjoy night life, avoid night crime," he said.
"All that we ask people to do is watch how much they and their friends drink.
"Equally, pubs, clubs and anyone who sells alcohol has a huge responsibility to ensure people do not drink excessively, and, if they are under 18, do not drink at all."
Police also seized alcohol from 16 people in "no drinking" zones and issued 14 vice warnings.
The arrests were made across Bristol, South Gloucestershire, Bath and Somerset.
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