The public are being warned not to approach two desperate fugitives - because they might have fleas.
Companion raccoon Rosie is now all alone
Raccoons Bonnie and Clyde dug their way to freedom from their enclosure at The Ark Animal Sanctuary, near Evesham.
Animal care worker Ross Lawford told BBC News: "They may well have fleas and lice, so people should not try picking them up and cuddling them."
The animals, a brother and sister aged six months, left behind an older companion, Rosie, who opted to remain.
"They will eat anything," Mr Lawford said. "And they can look after themselves, but we would like them back."
Bonnie and Clyde are valued at £500 each.
Raccoons are native to North America and can survive equally well in urban or rural areas.
A West Mercia Police spokesman said: "Bonnie and Clyde are shy animals and will probably head for secluded woodland.
"They like quiet and are not expected to be seen in a built-up area."
Anyone spotting them is asked to contact their local police station.