Up to 100 firefighters have tackled a blaze near Birmingham city centre following reports of an explosion.
Twelve people had to leave the building
Emergency services received reports of an explosion at the Dubliner pub during Wednesday morning. The fire is being treated as arson.
A fire service spokesman said the building, which has bedsits on the upper two floors, was badly damaged.
Twelve people were moved out of the building and one man was taken to hospital after breathing in smoke.
The pub is next to Digbeth Coach Station and National Express customers are being advised to contact the company for travel details.
Digbeth High Street and nearby roads will be closed for most of the day.
Divisional officer Archie Weldon, of West Midlands Fire and Rescue, said the fire began shortly before 0430 BST.
He said: "We will probably be at the scene for much of the day. Scenes of crimes officers and fire investigation officers are starting to look into the cause.
"The building is pretty much destroyed on the inside. The fire was extensive on all floors."