More than 200 job losses have been announced by Goodyear Dunlop.
Goodyear say the job losses are due to "restructuring"
Most of the losses will be at the company's Tyrefort warehousing and sales subsidiary in Erdington in Birmingham.
The rest will affect the company's Motorway and High Q fast-fit tyre centres across the UK.
Goodyear Dunlop says it needs to make the 216 redundancies to remain competitive.
Andreas Niegsch, general manager of sales operation, said: "We need to
restructure our sales operations in order to become a more flexible, dynamic and
responsive organisation in a highly competitive marketplace.
"Since the alliance between Goodyear and Dunlop was announced in 1999, we
have undertaken significant restructuring of our UK manufacturing and logistics
operations as we integrated the companies.
"We are committed to investing in their future and building their market share in the UK.
"However, to do this we need to make it easier for our trade customers to deal with us."
But union leaders say the job losses are a bitter blow for the workforce which has already made sacrifices over pay and conditions.
They say they have no faith in the company's restructuring programme and warn there could be more redundancies.
High production costs
In January, Goodyear's head office in America warned staff to expect a bleak new year.
The company has been suffering from high production costs and a low European demand for tyres.
In a letter to staff around the world, Goodyear's new chief executive, Robert Keegan, warned of possible job cuts, production cutbacks or switching manufacturing to cheaper plants.
The company axed 180 jobs at its Wolverhampton plant in October last year after car tyre production was scaled back.
But at a recent meeting, the company's European managers gave assurances that the factory does have a future.
None of the remaining 1,100 workers there will be affected by the latest cuts.