The MP for Stafford is calling for guarantees from an engineering company that it will remain in the town after it announced redundancies.
More than 200 jobs are to go at Areva's St Leonard's site. The firm said the cuts were necessary to keep the company competitive in the world market.
Labour MP David Kidney and officials from Staffordshire County Council will meet management on Monday evening.
Union leaders have described the cuts as a massive blow to Stafford.
Areva bought the site from French engineering giant Alstom in late 2003.