Taxi drivers are to hand out free condoms to late-night passengers as part of a sexual health project.
Condoms can provide effective protection against many STIs.
Some 60,000 condoms will be available from Thursday as part of the Safe Ride Home scheme in East Sussex.
Supported by boxer Chris Eubank, it will be operated by Brighton-based Radio Cabs after 2200 BST on Thursdays, Fridays and Saturdays.
Those who request contraceptives will get a leaflet with advice on preventing sexually transmitted infections (STIs).
Former WBO super-middleweight champion Eubank, who lives in Hove, said: "I think this will encourage the young people of Brighton to have fun, but also behave responsibly.
"This thought provoking initiative is a simple, hard-hitting way of tackling a very serious issue."
A spokesman for the contraceptive manufacturer Trojan, which is providing the condoms for the scheme, said young people often found themselves on a night out without any condoms, leading them to take risks.
By making them available on the way home means there should not be any excuses, he added.
Chris Nutely, co-owner of Radio Cabs, said: "We look after thousands of passengers every week, mostly young people out socialising at night.
"If we can help make a difference then we're more than happy to help."
According to Trojan, one in nine people are believed to carry an STI.