A search has been launched for a man who suffers from Huntingdon's disease after he failed to arrive at a rendezvous point in the Peak District.
Mr Henshaw's condition may make him appear as if he is drunk
Peter Henshaw, 43, from Barnsley, left Torside Reservoir on Tuesday and was last seen by two runners following the Pennine Way at Clough Edge.
Police said they are concerned about his welfare as he has no food or map with him.
Six mountain rescue teams are working with officers to find Mr Henshaw.
Three search and rescue dogs, the Forestry Commission and the National Park Ranger Service have also joined officers from South Yorkshire and Derbyshire Police in the search.
A police spokeswoman said they are particularly worried about Mr Henshaw due to his illness.
She said: "He has difficulty communicating and walks with an unusual gait because of his medical condition. This often gives him the appearance of someone who is drunk."
Mr Henshaw had intended to follow the Pennine Way to Edale, where he would catch the train back to Barnsley via Sheffield.
He is described as 6ft tall and clean shaven with mousey brown hair and a Barnsley accent.
He was last seen wearing a red fleece jacket, dark blue shorts, a blue t-shirt and brown boots.