Scientists discover allergy cells

Scientists at Oxford University have made the discovery

Scientists at Oxford University say they have made an important new discovery about the cells in our bodies which trigger allergic reactions.

They have shown that once a mast cell has been activated, it chemically activates other mast cells.

These cells act together to create an allergic response.

Prof Anant Parekh said he hoped this discovery could help some of the 20 million people in the UK who currently suffer from allergies like asthma.

"Allergies in the UK have reached epidemic proportions in this country," said Prof Parekh.

"It's estimated that one in three people are affected by allergic reactions - and that figure is likely to grow," he added.

Exciting possibilities

Prof Parekh is leading a team which has investigated how cells in the nose respond to allergens like pollen, triggering extreme immune responses.

Joe Di Capite, a research student, is excited about the possibilities.

"We've just identified the nasal cavity as one area where allergies may start. However, the principle should work throughout the body - wherever the mast cells play a role in producing an allergic reaction," he said.

Marion Hopkins is allergic to citric acid and E additives

Oxfordshire pensioner Marion Hopkins is allergic to citric acid and E additives.

"I've had headaches since I was 21 year old," she said.

"This could make a lot of difference to me and millions like me. I'd be able to eat strawberries which I love, as well as cherries and raspberries. I haven't eaten one of those in years."

Scientists as well as sufferers hope the discovery of how allergies are triggered could mean better drugs which prevent reactions from happening, rather than simply treating the symptoms.