SmartWater has had a major impact on crime in the city, police have said'
Officials have said 50,000 properties being marked with SmartWater has made life harder for burglars.
Each container of SmartWater liquid has a unique chemical signature, meaning property can be traced to its owner.
It can also be used to prove if a suspected burglar has been in a property or handled stolen items.
Officers said SmartWater evidence had a 100% success rate in getting convictions and also protected homes were less likely to be targeted.
The substance was first introduced into Nottingham homes in 2001 and since 2006 it has been a central part of the Nottingham Crime & Drugs Partnership's neighbourhood anti-crime Week of Action programmes.
The official milestone will be reached at a house in Heathfield, Basford, and more residents are being urged to mark their goods.
Alan Given, Crime & Drugs Partnership Chief Executive, said: "As well as the efforts of the Burglary Reduction Team, local tenant and residents groups, Neighbourhood Watch and local neighbourhood teams have been integral to this 50,000 milestone being reached.
"Crime continues to fall in the city and the ever-expanding SmartWater footprint that stretches across the city has been pivotal in the huge reductions in burglary. We will continue to work with local people to ensure these reductions continue."
This page is best viewed in an up-to-date web browser with style sheets (CSS) enabled. While you will be able to view the content of this page in your current browser, you will not be able to get the full visual experience. Please consider upgrading your browser software or enabling style sheets (CSS) if you are able to do so.