Work will begin next month to build a new dialysis unit at Cromer and District hospital in north Norfolk.
Sagle Bernstein gave £11m to the hospital that cared for her sister
The new eight-bay renal dialysis unit will be transferable to the £25m hospital planned for the area.
The project will benefit from £500,000 from the Sagle Bernstein legacy - Mrs Bernstein left more than £11m to the hospital when she died five years ago.
It is hoped a clinical team will start training and testing out the unit from January 2006.
David Prior, chairman of the Norfolk and Norwich University Hospital Trust, said the unit would save patients having to make repeat trips to Norwich.
He said: "I am doubly glad we have been able to put to good use some of the late Sagle Bernstein's legacy for the benefit of patients across north Norfolk.
"Mrs Bernstein made a remarkable bequest and from next year Cromer hospital will be able to provide important new services as a result."
The dialysis unit will be located at the back of the hospital site.
Sagle Bernstein, a widow and a resident of Cromer, died in May 2000 aged 82.
She left £11.4m to Cromer Hospital in thanks for the way staff cared for her dying sister in 1998.
Her husband had business interests in Britain and America.