Plans for Everton Football Club's new stadium in Kirkby, have officially been submitted to the local authority.
Kirkby Residents Action Group say they will call for a public inquiry
The application for the 50,000-seat ground, a joint venture with retail giant Tesco which will cost £400m, has been received by Knowsley Council.
The plans have been opposed by some Kirkby residents as well as people who believe Everton Football Club should remain in Liverpool.
The proposal also features the construction of 50 retail outlets.
The stadium and superstore plan, is also being pitched as an opportunity to regenerate the existing town centre.
This will see the development of leisure facilities such as hotels, bars and restaurants and investment in the existing Kirkby Market.
Keith Wyness, chief executive of Everton Football Club said: "This represents the next, key stage in what has been a complex and demanding process.
"We remain very optimistic about what is hugely-ambitious and significant project."
The application also details infrastructure and public improvements to Kirkby with around £10m earmarked for road improvements and further funding for boundary treatments designed to lessen the impact of the stadium on nearby neighbourhoods.
But Kirkby Residents Action Group oppose the plans claiming it would create a huge volume of match day traffic, impact on the environment and create a loss of green space
Tony Fletcher, Tesco public affairs manager, said: "We have been working on the Destination Kirkby planning application for the past ten months and we believe that this is a once-in-a-lifetime opportunity to create a development of truly international significance in the heart of Kirkby.
"We have consulted widely on our suggestions and have received valuable feedback not least from the people of Kirkby who have attended exhibitions and meetings with us."
If the application is successful developers hope to begin work later in the year.