The anniversary of the meeting which fanned the post war winds of change in Africa is being honoured on Friday.
Leading anti colonial campaigners attended the conference
Manchester Council is remembering the 60th anniversary of the Pan African Conference held in All Saints, Manchester from 15 to 21 October 1945.
Many of the men who led the independence movements in Africa - and later became the first post colonial leaders - attended the congress.
A town hall reception will be held with guests including African dignitaries.
Coun Val Stevens, deputy leader of Manchester City Council, said: "The Council is delighted to acknowledge the 60th anniversary of this historic event.
"It is particularly fitting that we should celebrate this occasion during Black History Month, a time for recognition of struggles for freedom, peace and equality for all people."
The conference attracted 90 ninety delegates - 26 from all over Africa - including a number of men who were to become political leaders in their countries, such as Hastings Banda, Kwame Nkrumah, Obafemi Awolowo and Jomo Kenyatta.
It was also attended by the wife of Marcus Garvey, the inspiration behind many civil rights movements and Trinidadian radical George Padmore.