One of the busiest stations in the hub of London's financial district will be closed for 10 days as an old bridge is demolished, Transport for London said.
Liverpool Street station will remain shut from 23 December until the early hours of 2 January.
The 120-year-old dilapidated bridge lies in the path of the planned extension of East London Tube route.
TfL said the work is "vital" and will affect very few people as offices will be closed during the holiday period.
Julie Dixon from TfL said: "This work is vital to the completion of the East London Line.
"We are offering various alternative routes and are letting everyone know in good time."
Ms Dixon added residents who will be affected due to the demolition work are being informed, consulted and will be adequately compensated.
The demolition is part of a £1.4bn investment into the rebuilding and expansion of the train route.