Tube users who may have had one too many at Christmas parties are being urged to take care on their way home.
The campaign will target 40 London Tube stations
One person died and there were 406 other alcohol-related injuries on the network last December and January.
The "Take a drink, take the Tube, but take care" campaign also asks passengers to show London Underground (LU) staff respect.
Posters will be put up and extra police patrols will take place at 10 central London stations.
In previous years people who have been drinking have tried climbing onto the tracks to pick up dropped belongings, have wandered into tunnels looking for a toilet and fallen down escalators.
Alcohol-related injuries at Tube stations last December and January
Oxford Circus: 26
Leicester Square: 25
London Bridge: 23
Seven Sisters: 21
Charing Cross: 13
LU's chief operating officer, Mike Brown said: "We want Londoners and visitors to enjoy the festive season and we want them to take the Tube, as a safe and reliable way to get home.
"However, at this time of year, Tube staff have to deal with the tragic results of accidents more often than usual. This can be a very harrowing experience for passengers and staff involved.
"Accidents do happen and we certainly don't want to be killjoys. If you have been out for a drink it makes sense to take the Tube home.
"We wish all our customers a great festive season. We also hope that it will be a safe one. "