Four police officers have been arrested on suspicion of corruption, according to Scotland Yard.
One woman and three men are being held after two separate investigations following tip-offs from colleagues.
Three are attached to CID units in Tower Hamlets, east London, and the fourth was working away from the units.
The allegations range from a "corrupt relationship" with a suspected criminal, to misconduct and conspiracy to pervert the course of justice.
A 44-year-old man from Dagenham, east London, has also been arrested.
Two separate investigations
Tower Hamlets commander Chief Superintendent Mark Simmons said: "These are serious allegations and it is essential that they are investigated thoroughly.
"I am pleased that officers on the borough felt able to raise their concerns
regarding the actions of a small number of their colleagues."
He said the vast majority of officers acted to the "highest standards
of honesty and integrity".
The investigation is being led by Detective Chief Inspector Ian Sweet, who said the arrests effectively brought together two separate investigations.