Madeleine McCann's father Gerry has returned to work nearly six months after his daughter's disappearance.
Mr McCann, a consultant cardiologist at Leicester's Glenfield Hospital, is expected to resume his duties by working three half-days a week.
Madeleine, of Rothley, Leics, vanished from a holiday apartment in Portugal on 3 May, days before her fourth birthday.
Mr McCann said he was pleased to be returning to work and was very grateful for all the support he had received.
"Kate and I have always said that if it ever got to six months that we didn't want to be looking back and wishing that we had done something that might influence our search for Madeleine. I think we're at that point now," said Mr McCann.
"Everything that we could have done personally, I think we have done. We've got an infrastructure and support system behind us now.
"And to be honest, unless Madeleine is found we're not expecting any developments in the near future."
He added the family wanted to "get back to some sort of normality".
Doug Skehan, clinical director at Glenfield Hospital, said he was confident Mr McCann was ready to return to work.
Madeleine has been missing for almost six months
He said: "We have seen the very great distress and pressure that Gerry and Kate have had to endure and have been very impressed with Gerry's composure and dignity.
"As with anyone who has had a long leave of absence, the return to work has to be carefully judged and phased. I think Gerry's medical family will welcome him back warmly and compassionately."
Mr McCann will be working half days and will not have direct contact with patients - carrying out academic work and MRI scans - until both he and his employers feel he is ready.
Kate McCann has a job as a part-time GP in Melton Mowbray but as yet has no plans to return to work.
A church service will be held in Rothley on Saturday to mark six months since Madeleine's disappearance.
Mr and Mrs McCann were named as arguido (suspects) in the case by Portuguese police and have been on unpaid leave since May.