The race is 50 laps around the town
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Elite race cyclists from across Europe are meeting in Lancashire for the start of the Ultraframe Cycling Grand Prix.
Cyclists taking part will compete in a 50-lap, 900m race around Clitheroe town centre on Wednesday evening.
Graham Jagger, of Ribble Valley Council, set up the event and said the town is one of only 10 venues in the UK to host a grand prix.
Cyclists taking part include Olympians Rob Hayles and Chris Newton, and some of the UK's top road riders.
Hayles won a gold medal for Great Britain when he won the men's Madison - a track race - with Mark Cavendish, at the World Track Championships in California earlier this year.
The Clitheroe feature race will be one of the deciding rounds of the National Elite Series.
Ribble Valley Council will use the day to launch its Cycling Strategy to encourage more people to take up the activity in the borough.