Liverpool was the European Capital of Culture in 2008
A bid for Hull and East Yorkshire to become the UK City of Culture in 2013 has been submitted to the government.
Officials behind the bid said they believed they had "created an unstoppable force for developing the area's fortunes".
Competition comes from about 20 places in the UK, including Yorkshire neighbours Sheffield and Barnsley.
A shortlist of successful cities will be released by the Department for Culture, Media and Sport in February.
Hull's bid has been put together by Hull City Council and East Riding of Yorkshire Council, and regional development agencies Hull Forward and Visit Hull and East Yorkshire.
In a statement Hull City Council said: "Whether or not the bid is successful, the process of creating it has focused the minds and resources of those taking part".
It said that the area's bid was based on Hull and East Yorkshire's "unrivalled combination of coast, city and countryside, its rich heritage and its unique personality".
The contest was thought up following the success of Liverpool's role as European Capital of Culture in 2008.
The winner could host events such as the Turner Prize, BBC Sports Personality of the Year and the Brits.