Motorists face weeks of disruption with plans to work on a bridge on the A46 in southern Warwickshire.
Warwick residents have been campaigning for years for a quieter surface on the dual-carriageway, yards from houses.
The scheme will see a new barrier and safety fence to reduce noise and increase safety on the Warwick Bypass.
The 10-week scheme starts on Monday, with most of the work in the daytimes on a one-mile stretch around the Grand Union Canal bridge, west of Warwick.
Traffic will be reduced to one lane on each carriageway with a 50mph limit. It will also affect access at the Birmingham Road Interchange.
Paul Davies, Highways Agency route sponsor, said: "Once completed the environmental barrier on the southbound carriageway will reduce noise from passing traffic for local residents.
"By introducing a new safety barrier we will be improving the bridge to protect both road and canal users."