The world-famous seeds firm Unwins has announced it will close its headquarters in Cambridgeshire.
Unwins is well-known to gardeners
The firm was established in Histon more than 100 years ago, but it said it makes commercial sense to operate one site rather than two.
The Histon site will close in the next six months and the work will move to another location in Chester, Cheshire.
About 50 jobs will be lost at Histon, which has a trial ground for sweet peas and other flowers and vegetables.
Staff at Histon are said to be upset about the decision to shut down. One worker told BBC Look East: "It's like one big family here; nobody wants to leave."
The firm was started in 1903 by WJ Unwin, and now manufactures 800 different varieties of seeds, which are shipped worldwide.
The company has a total of about 135 staff, including those at Histon.