A Bristol couple and their 10 children, are being evicted from their council home after complaints from neighbours going back 16 years.
The pair refused to go on a family support programme
Sarah Norkett, her partner John Hodgkins and their children must leave the house in Sea Mills by the end of the day.
Bristol City Council has served a possession order on the property.
A spokesman said the family had refused to take part in a project aimed at reducing anti-social behaviour.
Councillor for community safety, Gary Hopkins, said: "The city council, the police and other authorities have put a huge amount of effort in trying to resolve this problem."
He said a family support project in Bristol had been "immensely successful" and many problem families had been helped to reduce anti-social behaviour.
"This particular family declined to take part," said Mr Hopkins. If the family ends up homeless, an application can be made to the council for a new place to live.
But, if the council takes the view the family made itself deliberately homeless, it is not obliged to rehouse them.