Kleeneze is to close its headquarters in Warmley, Bristol with the loss of up to 312 jobs and re-locate to Accrington, Lancashire.
The announcement follows a comprehensive review of operations after its purchase by Findel plc.
Kleeneze said it anticipates "a significant number of positions will be created at the new location". Current staff will be offered relocation.
Kleeneze sells household cleaning products by catalogue.
Findel set about a review of the distributor network, head office functions, warehousing and distribution to consider how best to operate and expand the business.
The result has been to show that greater integration with Findel's existing facilities at Accrington will lead to enhanced customer service.
It is anticipated that the move of the head office functions will take place by the summer of 2007 with the warehouse move yet to be confirmed but will either be by the summer of 2007 or the spring of 2008.
The firm has gone from a turnover of less than £20m to approximately £100m within the past eight years.