Bus drivers on Wearside have voted to hold a one-day strike on Monday in a dispute over pay.
Go North East staff working at the company's depots in Sunderland and Washington have turned down a two 2% pay rise offer.
A spokesman for the firm said the offer was "more than reasonable" in the current recession.
Details on expected service disruption in both areas are available on the company's website.
Martin Harris, commercial manager of Go North East, said: "It's very unfortunate for our customers and we're very concerned to make sure we minimise the disruption for them.
"We've put together as much service as we can. We have a skeleton service providing a half-hourly service on all the most popular routes operated by these depots."
A reduced £1 flat fare has been introduced on the affected routes because of the expected inconvenience, he added.
Brian Anderson from Unite said: "In any industrial action the general public often suffer.
"That's not our intention. Our disagreement is with the company but we are aware they will be inconvenienced with this action."