Police broke down doors at dozens of homes in Southampton
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Fifty-one people have been charged following a series of police raids across London, Berkshire, Hampshire and the West Midlands.
About 800 police officers raided 55 homes in London, Southampton, Slough, and Solihull, arresting 51 people.
Since last Wednesday's operation three more men have been detained.
The charges against the 51 include supplying Class A drugs and firearms. Twenty will go before magistrates in Southampton - 31 appeared on Thursday.
The raids at dawn on Wednesday - codenamed Operation Phoenix - were the result of an 18-month investigation by Hampshire Constabulary's Serious and Organised Crime Unit.
The operation was the biggest ever pre-planned raid by Hampshire Constabulary.
Earlier, Assistant Chief Constable Steve Watts described the operation as "an extremely successful piece of police work".
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