Heavy rain and overnight winds have brought flooding and landslides to roads and rail links in the east.
Some roads in St Neots, Cambridgeshire, are blocked
Two lorries became stuck in deep water on the A11 at Wymondham, in Norfolk, and a third crashed into them blocking the road. No one was injured.
A landslide also blocked Rogues Lane at Papworth Everard in Cambridgeshire.
Residents of Walton Park, in Milton Keynes, awoke to find homes surrounded by flood water up to 4ft deep, and trains in Bedfordshire have been hit.
Church Lane at Bocking, near Braintree in Essex is blocked and Silverlink has replaced trains with buses between Bletchley and Bedford due to floods.
First Capital train services in Bedfordshire are running up to 20 minutes late because of water on lines.
Parts of Walton Park in Milton Keynes are also under water
The A1101 Wash Road in Welney on the Norfolk-Cambridgeshire border is also closed because of flooding.
And the A149 at Brancaster in North Norfolk and the A1135 at Yaxham near Dereham are both flooded.
Sgt Julian Roots from Norfolk Police said problems were likely to get worse as more people took to the roads during the day.
In Cambridgeshire there is heavy surface water on the A1 at St Neots and some surrounding roads are blocked by floods.
The A14 and nearby roads at Longstanton are also affected, with police advising drivers to take extra care because of deep surface water.