The mother of missing four-year-old Madeleine McCann broke down in a Spanish TV interview as she appealed for help to find her daughter.
Madeleine's parents were declared official suspects in September.
She told the Antena 3 station she felt "sad and lonely" without Madeleine.
Kate McCann said she was as confident her daughter would be found alive now as she was when she went missing in Portugal on 3 May.
Mrs McCann, and husband Gerry, were giving their first TV interview since being named as official suspects.
They were made "arguidos" at the start of September.
Madeleine, from Rothley, Leicestershire, vanished from the family's holiday apartment in Praia da Luz days before her fourth birthday.
GP Mrs McCann, 39, became emotional towards the end of the interview, recorded on Tuesday and due to be broadcast on Wednesday night.
"I feel anxious she is not with us," she said.
When asked about the last time she saw Madeleine alive, she replied: "She was very happy and very loving and I know Madeleine was very happy with her life.
"She is special."
She said she thought her daughter could be held by someone in their own house.
"As Madeleine's mummy, I feel in my heart that she is there.
"I don't know how anyone could harm anyone as beautiful as Madeleine. I don't mean her appearance, I mean as a beautiful person."
Asked how Madeleine's brother and sister - two-year-old twins Amelie and Sean - were coping, Mrs McCann said: "The hardest thing for me is when they say, 'When is Madeleine coming back home'?
"We have to say, 'we don't know but everyone is looking for her'."
Mr McCann described the last time he saw Madeleine - at 2105 when he checked on her before returning to the nearby tapas bar where he and his wife were dining with friends.
"I was the last to see her," he said.
"I saw her and thought how beautiful she was and thought how lucky I was to be a father of three children," he added.
Mr McCann, a 39-year-old cardiologist, said the couple wanted to appeal to "the people of Spain, Portugal and North Africa" for their help in finding Madeleine.
"As her parents we want people to try to help reunite our lovely four-year-old girl with her parents."
He said he was confident he and his wife would be cleared of any involvement in the disappearance and that "getting our daughter back" was the only thing that mattered.
A confidential 24-hour phone line, based in Spain and manned by private investigators, has been set up.
The couple's spokesman Clarence Mitchell said the initiative had received the backing of Portuguese police.